NFL Week 4 Fantasy Football Injury Report Friday WR

Bottom Line Up Front at WR

Justin Jefferson (MIN, ankle) is out and Terry McLaurin (WAS) picked up a brand-new hamstring issue on Friday — a real gut-punch for managers who thought his report was clean. Philadelphia is down both outside receivers (DeVonta Smith, Marquise Brown) on a short week, and Mike Evans is dealing with a new rib injury in San Francisco.

This week’s WR report covers 30 players: 1 already played this week, 13 out, 10 questionable, 3 no final tag yet (monday-night clubs), 3 cleared / no game-status designation.

Who is on this report?

Chris Moore (BAL), Zay Flowers (BAL), DJ Moore (BUF), Keon Coleman (BUF), Chris Brazzell II (CAR), Jalen Coker (CAR), Xavier Legette (CAR), Colbie Young (CIN), Tylan Wallace (CLE), Jayden Reed (GB), Jayden Higgins (HOU), Nico Collins (HOU), Ashton Dulin (IND), Keenan Allen (IND), Brenen Thompson (LAC), Ladd McConkey (LAC), Puka Nacua (LAR), Caleb Douglas (MIA), Justin Jefferson (MIN), Barion Brown (NO), Adonai Mitchell (NYJ), DeVonta Smith (PHI), Marquise Brown (PHI), Brandon Aiyuk (SF), Khadarel Hodge (SF), Mike Evans (SF), Ricky Pearsall (SF), Chris Godwin Jr. (TB), Jalen McMillan (TB), Terry McLaurin (WAS)

What changed since Week 3

NEW: Barion Brown (NO) — Newly appeared on this week’s injury report; was not on the Week 3 report
NEW: Brenen Thompson (LAC) — Newly appeared on the injury report this week
NEW: Chris Moore (BAL) — Newly appeared on the injury report this week; was not listed in Week 3
NEW: Colbie Young (CIN) — Newly appeared on the injury report for Week 4; not listed as injured in Week 3
DOWNGRADED: DeVonta Smith (PHI) — Downgraded – played through the same injury in Week 3 (MNF vs. Bears) but could not go this week after DNP all week
NEW: Justin Jefferson (MIN) — Newly injured — hurt during Week 3’s win over Tampa Bay (Sept 27), so this is his first missed game of the season and a new entry versus last week’s (Sept 25) clean report
NEW: Ladd McConkey (LAC) — Newly listed this week per available sources; was not on the Week 3 (Sept 25) report
NEW: Marquise Brown (PHI) — Newly out – no prior report of this injury
NEW: Mike Evans (SF) — Newly injured — hurt during the Week 3 win over Arizona, so this is a new addition to the injury report since last week
UPGRADED: Nico Collins (HOU) — Upgraded: missed Weeks 2 and 3 entirely, now cleared with no designation on the Week 4 report after progressing from limited to full practice participation
UPGRADED: Puka Nacua (LAR) — Upgraded — missed Weeks 2-3 with groin/hip soreness, now cleared with full Friday practice and no designation
NEW: Ricky Pearsall (SF) — Newly appeared on practice report this week; wasn’t previously a camp/injury story
NEW: Terry McLaurin (WAS) — Newly injured – was fully healthy and WAS’s leading receiver (141 yards this season) through Week 3; this issue arose only on the final practice day
NEW: Tylan Wallace (CLE) — Newly appeared on the injury report for Week 4; was not listed in Week 3
DOWNGRADED: Xavier Legette (CAR) — Downgraded to Out this week after DNP all practice week; played in Week 3
NEW: Zay Flowers (BAL) — Newly appeared on the injury report this week; was not listed in Week 3

Waiver wire: who gains if these names sit

If Adonai Mitchell (NYJ) can’t go — Isaiah Williams and Malik McClain see added offensive snaps; neither is a trustworthy fantasy play in a 12-team PPR league this week
If Caleb Douglas (MIA) can’t go — Jalen Tolbert and Ryan Miller see added snaps opposite Chris Bell; neither is more than a desperation-level PPR flex this week
If Tylan Wallace (CLE) can’t go — Malachi Corley and Isaiah Bond see a bump in offensive snaps; negligible ripple for CLE’s startable fantasy assets (Jeudy, Boston, Judkins, Fannin unaffected)
If Colbie Young (CIN) can’t go — Andrei Iosivas/Ke’Shawn Williams absorb extra snaps; no impact on Ja’Marr Chase, Tee Higgins, or Joe Burrow’s outlook
If Jayden Higgins (HOU) can’t go — His loss is why Houston traded for Kayshon Boutte (now starting) and expanded roles for Xavier Hutchinson and Jaylin Noel
If Brenen Thompson (LAC) can’t go — Negligible — Tre’ Harris remains the starting Right WR; deep/dynasty-league relevance only
If DeVonta Smith (PHI) can’t go — With Smith and Marquise Brown both out, Dontayvion Wicks and Makai Lemon are the clear beneficiaries in the Eagles’ receiving game, along with increased work for Saquon Barkley as a safety-valve target
If Marquise Brown (PHI) can’t go — His absence, combined with Smith being out, pushes Dontayvion Wicks and Makai Lemon into every-down roles this week
If Justin Jefferson (MIN) can’t go — Jordan Addison becomes the clear WR1/primary target for Minnesota this week; Jauan Jennings and Tai Felton see a bump in snaps/targets behind him
If Jayden Reed (GB) can’t go — Skyy Moore has been named the new No. 3 receiver behind Christian Watson and Matthew Golden and should see an increased role/target share; a drop/stash decision for fantasy rosters still holding Reed
If Jalen McMillan (TB) can’t go — His absence funnels extra snaps/targets to Tez Johnson and Kameron Johnson behind Egbuka and Godwin
If Xavier Legette (CAR) can’t go — John Metchie III is next in line on the right side; if Jalen Coker also sits, Metchie and Brycen Tremayne see expanded roles
If Chris Brazzell II (CAR) can’t go — None – not in the active WR rotation even when healthy
If Brandon Aiyuk (SF) can’t go — Zero current fantasy relevance; his absence is part of why San Francisco added Mike Evans and brought back Deebo Samuel this season

How to read this report

Designations reflect Friday, October 2, 2026 final injury/practice reports where filed.
Cleveland (CLE) and Pittsburgh (PIT) already played their Week 4 game Thursday night, October 1 — their entries reflect that completed game, not an upcoming one.
Atlanta (ATL) and New Orleans (NO) play each other Monday night, October 5 — some of their tags may not be finalized until Saturday.
“No Final Tag Yet” means a real injury concern exists but the club hasn’t filed (or confirmed) an official Week 4 game-status designation as of this report.

Already Played This Week (1)

These players’ games were already decided by Thursday night, before this Friday report — included for full-week context and any waiver-wire fallout.

Tylan Wallace (CLE, WR2 (backup, right side, behind Jerry Jeudy)) — OUT (a) Knee injury; did not practice at all during the short Week 4 prep week and was ruled out for Thursday night’s home game vs. Pittsburgh (played Oct. 1, Browns won 27-24).
Injury: Knee (since Within the Week 4 prep window (late Sept./Oct. 1, 2026); exact onset not specified in available reporting). Typical recovery: A knee injury serious enough to cause a full DNP week typically costs 1-3+ weeks depending on severity. Expected back: Unclear; status for Week 5 depends on practice participation once the Browns resume a normal week. Week 4 status: Did not play Week 4 (already final). Next 4 games: Low standalone fantasy value even healthy as Cleveland’s WR2 (behind Jeudy on the right side); Malachi Corley/Isaiah Bond absorb his snaps in the interim. Fantasy impact: Malachi Corley and Isaiah Bond see a bump in offensive snaps; negligible ripple for CLE’s startable fantasy assets (Jeudy, Boston, Judkins, Fannin unaffected)

Out (13)

Ruled out, on injured reserve, PUP, exempt, or suspended — not expected to play Week 4.

Chris Brazzell II (CAR, Deep-bench rookie WR – not currently on the active depth chart) — RESERVE-INJURED (c) Knee injury; on injured reserve with no return timeline given.
Injury: Knee (since Week 1-2, 2026 (approximate)). Typical recovery: Variable; no timeline reported, could range from several weeks to season-ending depending on severity. Expected back: Unknown – no timeline reported. Week 4 status: Out (IR) for Week 4. Next 4 games: No confirmed return timeline within this window. Fantasy impact: None – not in the active WR rotation even when healthy
Xavier Legette (CAR, WR2 (right side starter)) — OUT (a) Knee injury; did not practice all week and is officially ruled out for Week 4 vs. Detroit per CBS Sports’ Friday tracker.
Injury: Knee (since Week 3, 2026 (approximate)). Typical recovery: Knee sprains of this nature typically cost 2-4 weeks. Expected back: Approx. Week 6 (~Oct 18, 2026) per CBS Sports. Week 4 status: Out for Week 4 vs. Detroit. Next 4 games: Expected to miss roughly 2 more games before returning around Week 6. Fantasy impact: John Metchie III is next in line on the right side; if Jalen Coker also sits, Metchie and Brycen Tremayne see expanded roles
Colbie Young (CIN, WR2 (backup, right side, behind Tee Higgins)) — OUT (a) Knee injury; did not practice all week and is officially Out for Sunday’s Week 4 home game vs. Jacksonville.
Injury: Knee (since Within the Week 4 practice window (late Sept./early Oct. 2026); exact onset not specified in available reporting). Typical recovery: A knee injury producing a full DNP week typically costs 1-3+ weeks depending on severity. Expected back: Unclear; at minimum will miss Week 4, status beyond that depends on next week’s practice participation. Week 4 status: Out for Week 4 vs. Jacksonville. Next 4 games: Limited standalone fantasy relevance even healthy as Cincinnati’s WR2 behind Tee Higgins; Andrei Iosivas and Ke’Shawn Williams are next in line for snaps. Fantasy impact: Andrei Iosivas/Ke’Shawn Williams absorb extra snaps; no impact on Ja’Marr Chase, Tee Higgins, or Joe Burrow’s outlook
Jayden Reed (GB, Was a rotational WR2/3 receiver before the injury; no longer on the active depth chart) — RESERVE-INJURED (c) — placed on season-ending injured reserve on September 30, 2026 after a Week 2 neck injury that requires surgery. Done for the season.
Injury: Neck injury requiring surgery (head coach Matt LaFleur said he does not believe it is career-threatening; no further diagnosis disclosed) (since Week 2, 2026 (Packers’ win over the New York Jets)). Typical recovery: Season-ending; no return-to-play timeline has been given for this type of neck surgery. Expected back: Not expected back in 2026; no 2027 timeline given. Week 4 status: Out for the remainder of the 2026 season, including Week 4. Next 4 games: Out for all of them — season-ending injured reserve. Fantasy impact: Skyy Moore has been named the new No. 3 receiver behind Christian Watson and Matthew Golden and should see an increased role/target share; a drop/stash decision for fantasy rosters still holding Reed
Jayden Higgins (HOU, Was ticketed as a starting outside WR before the injury; not on the current active depth chart) — RESERVE-INJURED (c) Placed on season-ending injured reserve on August 21, 2026 after tearing his ACL in an August 18 joint practice against the Raiders. He was expected to start opposite Nico Collins in 2026 before the injury.
Injury: Torn ACL (left end zone landing during 11-on-11 red zone drill) (since August 18, 2026). Typical recovery: ACL reconstructions typically require roughly 9-12 months of recovery. Expected back: Not expected back in 2026; targeting a return for the 2027 season. Week 4 status: Out for the remainder of the 2026 season. Next 4 games: Out for all of these games; no snaps expected again in 2026. Fantasy impact: His loss is why Houston traded for Kayshon Boutte (now starting) and expanded roles for Xavier Hutchinson and Jaylin Noel
Brenen Thompson (LAC, WR2 (Right WR, backup to Tre’ Harris)) — OUT (a) quadriceps injury; did not practice this week and was ruled out on the Friday report.
Injury: Quadriceps strain (since Week 4 (exact date unclear from available sources)). Typical recovery: Quad strains typically require 1-3 weeks depending on grade of strain. Expected back: Possible return Week 5-6. Week 4 status: Out for Week 4 at Seattle. Next 4 games: Deep depth receiver; expected back within a few weeks but minimal standalone fantasy value even healthy. Fantasy impact: Negligible — Tre’ Harris remains the starting Right WR; deep/dynasty-league relevance only
Caleb Douglas (MIA, WR2 (Right WR)) — OUT (a) Ankle injury; did not practice all week and was ruled out for Week 4 at Minnesota.
Injury: Ankle (since Week 4, 2026 (exact onset date not specified in sources checked)). Typical recovery: Ankle sprains serious enough to cost a full week of practice typically sideline a player 1-3 weeks depending on severity. Expected back: Uncertain; no team timeline found in sources checked — monitor the Week 5 (Oct 11-12, 2026) injury report. Week 4 status: Will not play Week 4 at Minnesota. Next 4 games: Low standalone fantasy relevance even healthy, given Miami’s crowded, unproven WR room; worth only a deep-league speculative add if he returns to a clear role. Fantasy impact: Jalen Tolbert and Ryan Miller see added snaps opposite Chris Bell; neither is more than a desperation-level PPR flex this week
Justin Jefferson (MIN, WR1 (starter)) — OUT (a) sprained ankle suffered in the first half of Week 3’s win over Tampa Bay. Did not practice at all this week (Wed/Thu/Fri DNP) and is officially ruled out for Week 4 vs. Miami.
Injury: Ankle sprain (since September 27, 2026 (first half of the Week 3 win over Tampa Bay)). Typical recovery: Ankle sprains typically sideline a player 1-3 weeks depending on severity; no specific grade has been disclosed. Expected back: Earliest realistic return is Sunday, Oct. 11 at New Orleans (Week 5); Minnesota could also manage his workload further given the Week 6 bye. Week 4 status: Out for Week 4 vs. Miami Dolphins. Next 4 games: Targeting a Week 5 return at New Orleans at the earliest; some chance the team is cautious with him further since a Week 6 bye follows. Fantasy impact: Jordan Addison becomes the clear WR1/primary target for Minnesota this week; Jauan Jennings and Tai Felton see a bump in snaps/targets behind him
Adonai Mitchell (NYJ, WR1 (Left WR)) — OUT (a) Finger injury first flagged on Thursday’s injury report; did not practice and was ruled out for Week 4 vs. the Bears.
Injury: Finger (since Week 4, 2026 (first appeared on the Thursday, Oct 1, 2026 injury report)). Typical recovery: A finger sprain/dislocation typically costs only days to about 2 weeks, and many players return quickly once buddy-taped or splinted. Expected back: Uncertain; given the minor typical recovery window for this injury type, a Week 5 (Oct 11-12, 2026) return is plausible pending the team’s updated report. Week 4 status: Will not play Week 4 vs. Chicago. Next 4 games: Garrett Wilson remains the Jets’ unquestioned WR1 regardless; Mitchell’s absence bumps Isaiah Williams and Malik McClain into deep-league-only roles for one week if the injury proves short-term. Fantasy impact: Isaiah Williams and Malik McClain see added offensive snaps; neither is a trustworthy fantasy play in a 12-team PPR league this week
DeVonta Smith (PHI, WR1) — OUT (a) Hamstring injury; did not practice all week on Philadelphia’s short week and was ruled out on the Friday final report for the Rams game. He had been playing through a similar hamstring issue the prior week (started and played Monday Night Football vs. Bears) before it worsened.
Injury: Hamstring (since Originally flagged in practice the week of the Week 3 Monday night game (week of Sept 22, 2026); recurred/worsened heading into Week 4). Typical recovery: Hamstring strains typically cost 1-3 weeks; recurrence after playing through it can extend that. Expected back: Uncertain – at minimum this week, possibly into Week 5. Week 4 status: Out for Week 4 vs. Rams. Next 4 games: If it lingers beyond Week 4, expect a cautious, staggered practice ramp-up over the following 1-2 weeks. Fantasy impact: With Smith and Marquise Brown both out, Dontayvion Wicks and Makai Lemon are the clear beneficiaries in the Eagles’ receiving game, along with increased work for Saquon Barkley as a safety-valve target
Marquise Brown (PHI, WR2 (RWR, behind DeVonta Smith)) — OUT (a) Ankle injury (also referred to by his nickname “Hollywood” Brown); did not practice all week and was ruled out on Friday’s final report for the Rams game.
Injury: Ankle (since Week of Sept 29-Oct 2, 2026 (exact onset date unclear from reporting)). Typical recovery: Ankle sprains typically cost 1-3 weeks depending on grade. Expected back: Uncertain; no firm timeline reported. Week 4 status: Out for Week 4 vs. Rams. Next 4 games: Week-to-week; expect him back once the ankle settles, likely within 1-2 weeks. Fantasy impact: His absence, combined with Smith being out, pushes Dontayvion Wicks and Makai Lemon into every-down roles this week
Brandon Aiyuk (SF, Not on the active depth chart; listed as a reserve only) — RESERVE(c) On the 49ers’ reserve/left-squad list (Reserve-Did Not Report) rather than a standard weekly injury designation; technically still rehabbing a prior ACL/MCL tear but the team has stated he will not play for San Francisco again.
Injury: Right knee ACL/MCL tear (originally suffered in-season prior year) (since Prior season (original injury); has remained away from the team through 2026 offseason and into this season). Typical recovery: ACL/MCL reconstruction typically 9-12 months, but return is now a roster/relationship issue rather than a medical one. Expected back: Team has stated he will not return to the 49ers; any eventual reinstatement would require him to formally petition the league, which he reportedly has not done. Week 4 status: Not an option for San Francisco this week or going forward per GM John Lynch and HC Kyle Shanahan. Next 4 games: Not expected to play for the 49ers in any of the next 4 games; situation looks like a de facto departure from the team. Fantasy impact: Zero current fantasy relevance; his absence is part of why San Francisco added Mike Evans and brought back Deebo Samuel this season
Jalen McMillan (TB, WR depth piece (rotational outside/slot) – currently unavailable) — RESERVE-INJURED (c) Knee (PCL sprain); on injured reserve, not eligible to play Week 4.
Injury: Knee – PCL sprain (since Approx. Week 2-3, 2026 (exact date unclear)). Typical recovery: Isolated PCL sprains typically require 6-10+ weeks depending on grade. Expected back: Approx. Week 11 (~Nov 22, 2026) per CBS Sports. Week 4 status: Out (IR) for Week 4 and for several more weeks. Next 4 games: Not expected back within the next 4 games. Fantasy impact: His absence funnels extra snaps/targets to Tez Johnson and Kameron Johnson behind Egbuka and Godwin

Questionable (10)

Game-time decisions as of Friday’s final report — trust your waiver wire just in case.

Chris Moore (BAL, WR (starter, right side) opposite Bateman) — QUESTIONABLE (a) Ankle injury; limited practice participation ahead of Sunday’s Week 4 home game vs. Tennessee.
Injury: Ankle (since Week 4 practice week, 2026). Typical recovery: Ankle sprains typically take 1-3 weeks depending on grade. Expected back: Game-time decision for Week 4; likely clears if he progresses to a full practice before Sunday. Week 4 status: Questionable. Next 4 games: Low fantasy relevance even at full health as a low-target-share outside receiver; monitor for roster/streaming purposes only. Fantasy impact: Devontez Walker would move into the starting outside role if Moore sits; minimal fantasy ripple given Moore’s low target share
Zay Flowers (BAL, WR1 (slot)) — QUESTIONABLE (a) Hamstring, officially listed alongside a “not injury related – resting player” note; limited practice participation ahead of Sunday’s home game vs. Tennessee.
Injury: Hamstring (maintenance/rest designation, not described as a new acute injury) (since Week 4 practice week, 2026). Typical recovery: Hamstring tightness/strains of this type are typically day-to-day to 1-2 weeks. Expected back: Expected to be available Sunday barring a setback; game-time call. Week 4 status: Questionable, lean toward playing given the “resting player” framing. Next 4 games: No long-term concern expected; remains BAL’s clear slot/WR1 target earner. Fantasy impact: If he were to sit, rookie LaJohntay Wester would see expanded slot snaps, with Rashod Bateman and Chris Moore absorbing extra targets
DJ Moore (BUF, WR (Right WR, starter / primary target)) — QUESTIONABLE (a) Shoulder injury; limited in practice this week ahead of Sunday’s home game vs. New England.
Injury: Shoulder (since Week 4, 2026 (exact onset date not specified in sources checked)). Typical recovery: A shoulder sprain/AC joint issue that allows limited practice participation typically does not force a missed game, though it can be managed on a reduced-snap basis. Expected back: Game-time decision for Week 4; full clearance timeline not specified in sources checked. Week 4 status: Questionable for Week 4 vs. New England; expected to be a game-time call. Next 4 games: As Buffalo’s primary veteran target leader, expect him to play through this unless the team’s final report escalates; monitor the shoulder on a weekly basis. Fantasy impact: If he sits, Keon Coleman and Khalil Shakir absorb the bulk of his vacated targets, with Joshua Palmer and Skyler Bell seeing deep-league-only snap bumps
Keon Coleman (BUF, WR (Left WR, starter)) — QUESTIONABLE (a) Ankle injury; limited in practice this week ahead of Sunday’s home game vs. New England. Trending toward playing but not a lock.
Injury: Ankle (since Week 4, 2026 (exact onset date not specified in sources checked)). Typical recovery: A limited-practice ankle issue that doesn’t escalate to Doubtful/Out typically costs a player little to no missed game time, though snap count can be reduced. Expected back: Game-time decision for Week 4; full clearance timeline not specified in sources checked. Week 4 status: Questionable for Week 4 vs. New England; expected to be a game-time call. Next 4 games: If he plays through it, expect a normal complementary-WR role alongside DJ Moore and Khalil Shakir; worth re-checking the practice report each week this ankle is listed. Fantasy impact: If he sits, Joshua Palmer is the direct backup at his WR spot, with DJ Moore and Khalil Shakir absorbing additional target share
Jalen Coker (CAR, Slot WR (WR3 in base package)) — QUESTIONABLE (a) Quadriceps injury; limited practice participant Thursday, carrying a Week 4 Questionable tag vs. Detroit per CBS Sports’ Friday tracker.
Injury: Quadriceps (note: this is a new/different issue from the ankle injury he was managing in Weeks 2-3) (since Week 4 practice week (~Oct 1, 2026)). Typical recovery: Quad strains of this type typically cost 1-2 weeks if mild. Expected back: Game-time decision for Week 4; no extended absence currently projected. Week 4 status: Questionable for Week 4 vs. Detroit. Next 4 games: If he plays through it, expect his normal slot role; a setback would elevate Metchie III and Tremayne. Fantasy impact: If he sits, Legette’s and Coker’s absences together would push significant slot/outside volume to John Metchie III and Brycen Tremayne
Ashton Dulin (IND, Backup outside WR (right WR2)) — QUESTIONABLE (a) Carries an ankle injury on the Week 4 report despite a full Friday practice.
Injury: Ankle (since Week 4 (exact date of injury not specified in current reporting)). Typical recovery: Ankle sprains typically cost 1-3 weeks depending on severity; a full practice week points to a mild issue. Expected back: Week 4 (October 4, 2026) vs. Washington Commanders. Week 4 status: Questionable, but full practice participation points toward playing. Next 4 games: Expected to remain available in a depth/situational WR role barring setback. Fantasy impact: Low standalone fantasy relevance; mainly a thin-depth consideration if Keenan Allen were also out
Keenan Allen (IND, Starting outside WR (right WR1)) — QUESTIONABLE (a) Did not practice Friday, but the team’s own injury report flagged it as “not injury related – resting player” tied to a groin issue being managed rather than a new, acute injury.
Injury: Groin (veteran rest/maintenance, not an acute new injury per the club’s own notation) (since Week 4 (ongoing maintenance issue; no specific injury date identified in current reporting)). Typical recovery: Veteran rest/maintenance groin issues typically do not require missed games. Expected back: Week 4 (October 4, 2026) vs. Washington Commanders. Week 4 status: Questionable but trending toward playing given the rest-day framing. Next 4 games: Likely to keep playing through this as a managed veteran workload issue; worth a weekly practice-report check. Fantasy impact: If he sits, Ashton Dulin and Darius Slayton would see expanded routes/targets
Ladd McConkey (LAC, WR1 (Slot WR, starter)) — QUESTIONABLE (a) foot injury; Limited Participation in practice this week, officially Questionable per the Friday report.
Injury: Foot (since Week 4 (exact date unclear from available sources; a lingering issue that surfaced on this week’s report)). Typical recovery: Foot injuries vary widely — a sprain can resolve in 1-2 weeks, but ligament or plantar-fascia-type issues can linger 3-6+ weeks. Expected back: Game-time decision for Week 4; the Limited (not DNP) practice status suggests a real chance he plays. Week 4 status: Questionable for Week 4 at Seattle — trending toward available. Next 4 games: If he plays through it, expect a normal target share with some week-to-week injury-report volatility; a setback could push him toward IR. Fantasy impact: Derius Davis is the direct backup in the slot; Quentin Johnston and Tre’ Harris would see a target-share bump if McConkey sits
Mike Evans (SF, WR1 (left side, signed in free agency in 2026 after leaving Tampa Bay)) — QUESTIONABLE(a) Officially listed Questionable for Week 4 vs Denver with a ribs injury sustained in Week 3; did not practice Wed/Thu, limited Friday.
Injury: Ribs (since Week 3 (sustained in San Francisco’s win over Arizona)). Typical recovery: Rib injuries (non-fracture) typically cost 1-2 weeks; Shanahan said it is “not expected to be long-term”. Expected back: Game-time decision Week 4; likely available by Week 5 if held out. Week 4 status: Questionable — true game-time decision; HC Kyle Shanahan said “Hopefully we’ve got a shot”. Next 4 games: If he plays, expect a snap-count/workload caution; if he sits, DeMarcus Robinson and Khadarel Hodge see boosted targets on the perimeter. Fantasy impact: If Evans sits, DeMarcus Robinson is the clearest fantasy beneficiary for added target share, with Khadarel Hodge also in the mix
Terry McLaurin (WAS, WR1) — QUESTIONABLE (a) New hamstring issue that “popped up” in Friday’s (Oct 2) practice per NFL Network’s Tom Pelissero; a surprise, last-minute addition to the injury report that was not there earlier in the week. Game-time decision for the London game vs. Colts.
Injury: Hamstring (new, distinct from a prior-season quad injury) (since Friday, October 2, 2026 (practice)). Typical recovery: A mild hamstring strain discovered the same week can still allow a player to suit up; moderate strains cost 1-3 weeks. Expected back: Game-time decision for Week 4; if he plays, workload could be monitored. Week 4 status: Questionable – uncertain whether he plays Sunday in London. Next 4 games: If he plays through it Week 4, expect normal role; if it lingers, 1-2 weeks of downgraded practice participation are plausible. Fantasy impact: If McLaurin sits, Stefon Diggs and Deebo-type slot usage increase, with Dyami Brown and Jaylin Lane seeing more snaps – no clean 1-for-1 handcuff since he is the clear WR1

No Final Tag Yet (Monday-Night Clubs) (3)

Carries a real injury concern, but the club hasn’t filed (or confirmed) its final Week 4 tag yet — check back Saturday.

Barion Brown (NO, WR2 (right side, opposite Chris Olave)) — QUESTIONABLE (b) Hamstring injury; limited practice participant Thursday. NO’s game is Monday night (Oct 5), so this week’s designation may still be preliminary and could be updated on New Orleans’ Saturday injury report.
Injury: Hamstring (since Week 4 practice week (~Oct 1, 2026)). Typical recovery: Hamstring strains typically cost 1-3 weeks depending on grade. Expected back: Game-time decision for Monday night Week 4; no extended absence currently projected. Week 4 status: Questionable heading into Monday night vs. Atlanta; final tag may not be official until Saturday. Next 4 games: If he plays, expect a complementary WR2/3 role opposite Chris Olave; a setback would open snaps to Bryce Lance and Devaughn Vele. Fantasy impact: If he sits, Bryce Lance and Devaughn Vele would see increased snaps/targets behind Chris Olave
Khadarel Hodge (SF, WR (right side, WR2 behind DeMarcus Robinson)) — QUESTIONABLE(b) Appeared on the 49ers’ official practice report with a knee injury (DNP Wed and Thu); he was not among the three players the team announced as ruled Out for Week 4, but no confirmed final Friday tag was found in available team reporting.
Injury: Knee (since Week N (prior to Week 4; exact date not disclosed)). Typical recovery: unknown. Expected back: unknown. Week 4 status: Uncertain — on the practice report with a knee issue but not confirmed among the team’s Out designations; treat as a game-time watch. Next 4 games: Deep WR4/5 role regardless; limited standalone fantasy value even if he plays. Fantasy impact: Not fantasy-relevant in standard 12-team leagues either way
Ricky Pearsall (SF, WR (rotational depth piece, not currently listed among SF’s top perimeter targets on the depth chart used for this report)) — QUESTIONABLE(b) Not on the team’s formal Week 4 injury-report table in available reporting, but Kyle Shanahan confirmed Pearsall has knee soreness and did not practice Wednesday; Pearsall himself said he is confident he would play if the game were that day.
Injury: Knee (soreness) (since Week 3 or Week 4 practice (Shanahan was unsure of the exact play)). Typical recovery: Minor knee soreness typically does not cost game time. Expected back: Expected to play Week 4 per his own comments. Week 4 status: Likely to play; self-described as game-ready. Next 4 games: No long-term concern indicated; worth a practice-participation check in-season but not currently expected to miss time. Fantasy impact: Low-end flex/bench stash in deeper leagues given SF’s crowded WR room (Evans, Samuel, Robinson, Cowing ahead of him in target competition)

Cleared / No Game-Status Designation (3)

Managing something, but carries no game-status designation and is expected to play.

Nico Collins (HOU, WR1 (left WR)) — NO GAME-STATUS DESIGNATION (a) Not listed on the Friday injury report. Collins suffered a hamstring strain (reported as a low-grade/Grade 1 strain) on September 16, 2026, which cost him Weeks 2 and 3. He practiced on an increasing basis this week (limited Wed/Thu per some reports, full Friday per others) and multiple current sources agree he was off the final Week 4 report and full-go Friday.
Injury: Hamstring strain (since September 16, 2026 (Wednesday practice)). Typical recovery: Grade 1 hamstring strains typically sideline a player 1-3 weeks. Expected back: Week 4 (October 4, 2026) vs. Dallas Cowboys. Week 4 status: Expected to play and resume his normal role Week 4. Next 4 games: Expected to step back in as Houston’s clear WR1 with a full route tree; workload could still be lightly monitored in his first game back after a 2-game absence. Fantasy impact: With Collins active, Houston’s passing game funnels back through him; if he were to sit, Kayshon Boutte and Xavier Hutchinson would see the added target share
Puka Nacua (LAR, WR2/primary target (Rams’ top target alongside Davante Adams)) — NO GAME-STATUS DESIGNATION(a) Cleared with no game designation after Limited practice Wed/Thu and full participation Friday; officially “good to go” for Week 4 at Philadelphia.
Injury: Hip (previously also dealt with groin soreness) (since Week 2 (missed two games with groin/hip issue before Week 4)). Typical recovery: Soft-tissue hip/groin injuries typically sideline a player 1-3 weeks. Expected back: Returning Week 4 vs Philadelphia. Week 4 status: Expected to play and start Week 4. Next 4 games: Expected to resume full WR1 workload now that he has been cleared; monitor practice reps in following weeks for any setback. Fantasy impact: His return pushes Jordan Whittington and Konata Mumpfield back down the target share pecking order; no real waiver-add benefit since he’s playing
Chris Godwin Jr. (TB, Slot WR / WR2 in target share) — RESOLVED (b) Ankle; did not practice Wednesday but returned to a full practice Thursday and does not appear on the Friday Questionable/Out list, indicating he is good to go for Week 4 with no formal designation.
Injury: Ankle (since Week 4 practice week (~Sept 30, 2026)). Typical recovery: Minor ankle soreness of this type (DNP to full in two days) typically resolves within days. Expected back: Already resolved – expected to play Week 4. Week 4 status: Expected to play Week 4 vs. Green Bay, no injury designation. Next 4 games: No expected absences tied to this ankle issue. Fantasy impact: No impact expected – full workload anticipated

Sourcing: NFL.com official injury reports, team-issued injury reports, Ourlads depth charts, and beat-reporter coverage, as of Friday, October 2, 2026.